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Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Pseudo-dynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry

Isaac Esteban, Patrick Schmidt, Susana Temiño, et al.



Selected by Yen Tran

Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Joyce J. Thompson, Daniel J. Lee, Apratim Mitra, et al.



Selected by María Mariner-Faulí

Reconstructing human early embryogenesis in vitro with pluripotent stem cells

Berna Sozen, Victoria Jorgensen, Meng Zhu, et al.



Selected by Martin Estermann

Lactate Accelerates Mouse ES Cell Differentiation Towards the XEN Lineage

Mohamed I. Gatie, Tyler T. Cooper, Gilles A. Lajoie, et al.



Selected by Nozomu Takata

Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos

Zheng Guo, Jie Yao, Xu Zheng, et al.



Selected by Sophia Friesen

A spatially resolved single cell atlas of human gastrulation

Richard C.V. Tyser, Elmir Mahammadov, Shota Nakanoh, et al.



Selected by Martin Estermann

Mechanics regulate human embryonic stem cell self-organization to specify mesoderm

Jonathon M. Muncie, Nadia M.E. Ayad, Johnathon N. Lakins, et al.



Selected by Claire Simon & Sophie Morgani

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.



Selected by Pierre Osteil

Early neurulation recapitulated in assemblies of embryonic and extraembryonic cells

Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, et al.



Selected by Monica Tambalo

Defining totipotency using criteria of increasing stringency

Eszter Posfai, John Paul Schell, Adrian Janiszewski, et al.



Selected by Teresa Rayon

An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition

Evangéline Despin-Guitard, Navrita Mathiah, Matthew Stower, et al.



Selected by Claire Simon & Sophie Morgani

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