Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart
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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
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Monica Tambalo et al.
Pseudo-dynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry
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Yen Tran
Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates
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María Mariner-Faulí
Reconstructing human early embryogenesis in vitro with pluripotent stem cells
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Martin Estermann
Lactate Accelerates Mouse ES Cell Differentiation Towards the XEN Lineage
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Nozomu Takata
Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos
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Sophia Friesen
A spatially resolved single cell atlas of human gastrulation
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Martin Estermann
Mechanics regulate human embryonic stem cell self-organization to specify mesoderm
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Claire Simon & Sophie Morgani
Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization
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Pierre Osteil
Early neurulation recapitulated in assemblies of embryonic and extraembryonic cells
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Monica Tambalo
Defining totipotency using criteria of increasing stringency
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Teresa Rayon
An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition
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Claire Simon & Sophie Morgani