Search results

Circumvention of common labeling artifacts using secondary nanobodies

Shama Sograte-Idrissi, Thomas Schlichthaerle, Carlos J. Duque-Afonso, et al.

Selected by 03 April 2020

Mariana De Niz

Discussion

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Selected by 02 April 2020

Mariana De Niz

Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors

Jeremy J. Work, Onn Brandmann

Selected by 27 March 2020

Sandra Malmgren Hill

Discussion

Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Ryan R. Cupo, James Shorter

Selected by 13 February 2020

Tessa Sinnige

Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function

Heike Blockus, Sebastian V. Rolotti, Miklos Szoboszlay, et al.

Selected by 02 January 2020

Ana Dorrego-Rivas

Discussion

Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates

Poonam Thakur, Kelvin Luk, Jochen Roeper

Selected by 18 December 2019

Jessica Xie

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.

Selected by 27 October 2019

Tessa Sinnige

The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain

Alessia Peduzzo, Sara Linse, Alexander K. Buell

Selected by 20 September 2019

Tessa Sinnige

Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Richard J. Wheeler, Hyun O. Lee, Ina Poser, et al.

Selected by 30 August 2019

Madhuja Samaddar

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

Rui Jia, Juan S. Bonifacino

Selected by 18 July 2019

Sandra Malmgren Hill

Discussion

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Discussion

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Discussion