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Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan



Selected by Connor Rosen

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.



Selected by Kristina Kuhbandner

1

FERONIA regulates FLS2 plasma membrane nanoscale dynamics to modulate plant immune signaling

Julien Gronnier, Christina M. Franck, Martin Stegmann, et al.



Selected by Marc Somssich

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.



Selected by Jennifer Ann Black

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.



Selected by Louise Fraser

1

Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, et al.



Selected by Nicola Stevenson

1

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Alessandro Stirpe, Nora Guidotti, Sarah Northall, et al.



Selected by Yasmin Lau

1

Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei

Simona Amodeo, Ana Kalichava, Albert Fradera-Sola, et al.



Selected by Jennifer Ann Black

1

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

Sara M. Nowinski, Ashley Solmonson, Scott F. Rusin, et al.



Selected by Berrak Ugur, Aakriti Jain

1

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

AND

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose



Selected by Gabriel Aughey

2

FUS gene is dual-coding with both proteins united in FUS-mediated toxicity

Marie A. Brunet, Jean-Francois Jacques, Sonya Nassari, et al.



Selected by Madhuja Samaddar

1

The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics

Andrea Serra-Marques, Ronja Houtekamer, Dorine Hintzen, et al.

AND

NuMA interaction with chromatin is vital for proper nuclear architecture in human cells

Ashwathi Rajeevan, Riya Keshri, Sachin Kotak



Selected by Dey Lab

2

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