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High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

AND

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.

Selected by 10 August 2020

Kirsty Ferguson

Cell Biology

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Selected by 27 July 2020

Zhang-He Goh

Pharmacology and Toxicology

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Selected by 25 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by 22 May 2020

Kirsty Ferguson

Developmental Biology

Coupled active systems encode emergent behavioral dynamics of the unicellular predator Lacrymaria olor

Scott M. Coyle, Ellie M. Flaum, Hongquan Li, et al.

Selected by 29 January 2020

Mariana De Niz

Biophysics

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

Aditi Kulkarni, Wanqin Yu, Alex Moon, et al.

Selected by 12 December 2019

Yasmin Lau

COMET: A toolkit for composing customizable genetic programs in mammalian cells

Patrick S. Donahue, Joseph W. Draut, Joseph J. Muldoon, et al.

Selected by 29 September 2019

Zhang-He Goh

Synthetic Biology

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.

Selected by 20 August 2019

Nicola Stevenson

Molecular Biology

engineering Phage Host-Range and Suppressing Bacterial Resistance Through Phage Tail Fiber Mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Synthetic Biology

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Molecular Biology

Aequorea victoria’s secrets

Gerard G. Lambert, Hadrien Depernet, Guillaume Gotthard, et al.

Selected by 07 July 2019

Marc Somssich

Biochemistry

On-demand, cell-free biomanufacturing of conjugate vaccines at the point-of-care

Jessica C. Stark, Thapakorn Jaroentomeechai, Tyler D. Moeller, et al.

Selected by 03 July 2019

Zhang-He Goh

Synthetic Biology