Search results

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Selected by 21 July 2023

Kritika Mehta

Discussion

ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

Aleksandar Bartolome, Julia C. Heiby, Therese Dau, et al.

Selected by 01 May 2023

Aniruddha Das

Discussion

Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation

Evandro A. De-Souza, Maximillian A. Thompson, Rebecca C. Taylor

Selected by 05 December 2022

Chee Kiang Ewe

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by 20 May 2021

Eric McGregor

Discussion

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

Selected by 18 May 2020

Teresa Rayon

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Selected by 01 May 2020

Kirsty Ferguson

Discussion

Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis

Peter Shyu, Wei Sheng Yap, Maria L. Gaspar, et al.

Selected by 26 April 2020

Madhuja Samaddar

Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors

Jeremy J. Work, Onn Brandmann

Selected by 27 March 2020

Sandra Malmgren Hill

Discussion

Aging is associated with a systemic length-driven transcriptome imbalance

Thomas Stoeger, Rogan A. Grant, Alexandra C. McQuattie-Pimentel, et al.

Selected by 04 September 2019

Monika S. Magon

Discussion

LTK is an ER-resident receptor tyrosine kinase that regulates secretion

Federica G. Centonze, Veronika Reiterer, Karsten Nalbach, et al.

Selected by 12 April 2019

Nicola Stevenson

A non-canonical arm of UPR^ER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Selected by 07 January 2019

Sandra Franco Iborra

A non-canonical arm of UPR^ER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Selected by 17 December 2018

Sandra Malmgren Hill

Discussion