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Profilin 1 maintains cell cycle fidelity to prevent unscheduled genome doubling and polyploidy in cancer

Federica Scotto di Carlo, Sharon Russo, Simon Gemble, et al.

Discussion

Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis

William N. Colgan, Luke W. Koblan, JoAnne Villagrana, et al.

Discussion

The Endocannabinoid System’s Contribution to Placebo Analgesia

Rossi Tomin, Kevin Murray, Georgia E. Hadjis, et al.

Discussion

Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 367,988 people using natural language processing

Matthew H Iveson, Mome Mukerjee, Emma M Davidson, et al.

Discussion

A Cell Size-Dependent Competition Between Geometry and Polarity Governs Nuclear and Spindle positioning in Early Embryos

Aude Nommick, Macy Baboch, Celia Municio-Diaz, et al.

Evolutionary landscapes of zygotic genome activation across animals

Israel Campo-Bes, Federica Mantica, Jon Permanyer, et al.

No global collapse of food webs across the Permian–Triassic Mass Extinction

Baran Karapunar, Tanya Strydom, Andrew P. Beckerman, et al.

Discussion

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

Electrophysiological correlates of conscious experiences during sleep: Lucid dreams, sleep paralysis, out-of-body experiences, and false awakenings

Nerea L. Herrero, Yohann Corfdir, Aylin A. Vázquez-Chenlo, et al.

Cooperation between cortical and cytoplasmic forces shapes planar 4-cell stage embryos

Silvia Caballero-Mancebo, Daniel Gonzalez Suarez, Janet Chenevert, et al.

KANK2 at focal adhesion regulates their maintenance and dynamics, while at fibrillar adhesions it influences cell migration via microtubule-dependent mechanism

Nikolina Stojanović, Anja Rac, Marija Lončarić, et al.

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.