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A non-canonical arm of UPR^ER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals

Salah Mahmoudi, Elena Mancini, Alessandra Moore, et al.

Systematic identification of human SNPs affecting regulatory element activity

Joris van Arensbergen, Ludo Pagie, Vincent FitzPatrick, et al.

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

Federico Germani, Daniel Hain, Denise Sternlicht, et al.

Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila

Charles A Seller, Chun-Yi Cho, Patrick H O'Farrell

Drosophila kinesin-8 stabilises kinetochore-microtubule interaction

Tomoya Edzuka, Gohta Goshima

Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells

Shumin Xia, Evelyn K.F. Yim, Pakorn Kanchanawong

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Superresolution architecture of pluripotency guarding adhesions

Aki Stubb, Camilo Guzmán, Elisa Närvä, et al.

Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells

Ina Hollerer, Juliet C Barker, Victoria Jorgensen, et al.

Lysosome exocytosis is required for mitosis

Charlotte Nugues, Nordine Helassa, Robert Burgoyne, et al.

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation

Joseph Massey, Yida Liu, Omar Alvarenga, et al.

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pigmentation pathway

Alexander Swoboda, Robert Soukup, Katharina Kinslechner, et al.