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A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

Selected by 15 June 2021

María Mariner-Faulí

Developmental Biology

Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, et al.

Selected by 21 April 2021

Alexander Ward

Genetics

H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

Cemil Kerimoglu, Linh Pham, Anton B. Tonchev, et al.

Selected by 05 April 2021

Ana Uzquiano

Cell Biology

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Selected by 17 February 2021

Sergio Menchero

Molecular Biology

Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque

Paul Cheng, Robert C. Wirka, Juyong Brian Kim, et al.

Selected by 12 January 2021

Debbie Ho

Cell Biology

Association analysis of repetitive elements and R-loop formation across species

Chao Zeng, Masahiro Onoguchi, Michiaki Hamada

Selected by 28 December 2020

Sree Rama Chaitanya

Genomics

Evolution of mouse circadian enhancers from transposable elements

Julius Judd, Hayley Sanderson, Cédric Feschotte

Selected by 15 December 2020

Miguel V. Almeida

Genomics

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, et al.

Selected by 11 December 2020

Irepan Salvador-Martinez

Bioinformatics

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

Simona Giunta, Solène Hervé, Ryan R. White, et al.

Selected by 10 December 2020

Sree Rama Chaitanya

Cell Biology

Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer

Eunhee Yi, Amit D. Gujar, Molly Guthrie, et al.

Selected by 28 October 2020

Sree Rama Chaitanya

Cancer Biology

Genome-wide maps of enhancer regulation connect risk variants to disease genes

Joseph Nasser, Drew T. Bergman, Charles P. Fulco, et al.

Selected by 30 September 2020

Jesus Victorino

Genomics

Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males

Kevin H.-C. Wei, Lauren Gibilisco, Doris Bachtrog

Selected by 16 September 2020

Hann Ng

Developmental Biology