Search results

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by 15 December 2023

Pierre Caron

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by 14 November 2023

Audrey Noireterre

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.

Selected by 08 November 2023

Benjamin Dominik Maier et al.

Discussion

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Selected by 18 October 2023

Isabella Cisneros

Discussion

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

Luyang Xiong, Irina Zhevlakova, Xiaoxia Z. West, et al.

Selected by 14 September 2023

Marina Schernthanner

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Discussion

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Aakanksha Jain, Benjamin M. Gyori, Sara Hakim, et al.

Selected by 05 July 2023

Patrick Penndorf

Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience

John W. Brooks, Vikas Tillu, Suzie Verma, et al.

Selected by 15 June 2023

Teodora Piskova

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Discussion

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Discussion