The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Selected by
14 November 2023
Audrey Noireterre

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
06 September 2023
Jessica Chevallier, Pierre Caron

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
15 May 2023
Jennifer Ann Black

Actin nucleators safeguard replication forks by limiting nascent strand degradation
Selected by
22 March 2023
Roberto Amadio

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis
Selected by
09 March 2023
Pierre Caron

Nuclear myosin VI maintains replication fork stability
Selected by
13 December 2022
Pierre Caron

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
Selected by
10 December 2020
Sree Rama Chaitanya

ARID1A regulates R-loop associated DNA replication stress
Selected by
05 December 2020
Sree Rama Chaitanya

Single-molecule live cell imaging of the Smc5/6 DNA repair complex
Selected by
26 June 2020
Jennifer Ann Black

RADX Sustains POT1 Function at Telomeres to Counteract RAD51 Binding, which Triggers Telomere Fragility
Selected by
25 June 2020
Upasana Roy

fork-seq: replication landscape of the Saccharomyces cerevisiae genome by nanopore sequencing
Selected by
27 April 2020
Jennifer Ann Black

Mutational signatures are jointly shaped by DNA damage and repair
Selected by
24 February 2020
Kerryn Elliott
