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Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Discussion

Sexually Dimorphic DNA Damage Responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.

Regulation of blood cell transdifferentiation by oxygen sensing neurons

Sean Corcoran, Anjeli Mase, Yousuf Hashmi, et al.

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Discussion

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

Discussion

Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis

Peter Shyu, Wei Sheng Yap, Maria L. Gaspar, et al.

Defining totipotency using criteria of increasing stringency

Eszter Posfai, John Paul Schell, Adrian Janiszewski, et al.

Calpain-2 regulates hypoxia/HIF-induced amoeboid reprogramming and metastasis

Veronika te Boekhorst, Liying Jiang, Marius Mählen, et al.

Discussion

Glucose metabolism distinguishes TE from ICM fate during mammalian embryogenesis

Fangtao Chi, Mark S. Sharpley, Raghavendra Nagaraj, et al.

Discussion

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.