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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepulveda, Xiang Li, Xiaojing Yue, et al.

Scalable and efficient generation of mouse primordial germ cell-like cells

Xinbao Ding, Liangdao Li, Jingyi Gao, et al.

Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction

Diego A. López, Aleah Griffin, Lorena Moreno Aguilar, et al.

Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition

Xiangyu Gong, Ryan Nguyen, Zehua Chen, et al.

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, et al.

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals

Victorya Richardson, Kai Zhang, Nora Engel, et al.

Synthetic memory circuits for programmable cell reconfiguration in plants

James P B Lloyd, Florence Ly, Patrick Gong, et al.

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Synthetic genetic circuits enable reprogramming of plant roots

Jennifer A. N. Brophy, Katie J. Magallon, Kiril Kniazev, et al.

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

Ryan J. Gleason, Christopher S. Semancik, Gitanjali Lakshminarayanan, et al.

Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc

Ioannis Nellas, K. Venkatesan Iyer, Juan M. Iglesias-Artola, et al.

Single-cell transcriptome analysis of embryonic and adult endothelial cells allows to rank the hemogenic potential of post-natal endothelium

Artem Adamov, Yasmin Natalia Serina Secanechia, Christophe Lancrin

Diverse mechanisms for epigenetic imprinting in mammals

Daniel Andergassen, Zachary D. Smith, John L. Rinn, et al.