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Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Selected by 09 December 2025

Inês Caiado

Immunology

Stress granules formed during different rna virus infections show remarkable plasticity and substantial virus-specific differences in their formation and composition

Reto M. Lang, Silvio Steiner, Jenna Kelly, et al.

Selected by 03 November 2025

Mohammed JALLOH

Cell Biology

Condensation of Sidekick at tricellular junctions organizes mechanical forces for cell-cell adhesion remodeling

Hiroyuki Uechi, Daxiao Sun, Yuki Saeki, et al.

Selected by 17 October 2025

Fatima Rafiq

Biophysics

Tandem duplication of serpin genes yields functional variation and snake venom inhibitors

Meilyn S. Ward, Matthew L. Holding, Laura M. Haynes, et al.

Selected by 09 October 2025

Daniel Osorno Valencia, Marcus Oliveira

Evolutionary Biology

FUS Mislocalization Rewires a Cortical Gene Network to Drive 2 Cognitive and Behavioral Impairment in ALS

Raphaelle CASSEL, Félicie LORENC, Aurélie BOMBARDIER, et al.

Selected by 14 July 2025

Taylor Stolberg

Neuroscience

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation

Marika Oksanen, Francesca Mastropasqua, Krystyna Mazan-Mamczarz, et al.

Selected by 24 June 2025

Candy Rutihinda et al.

Molecular Biology

trna synthetase activity is required for stress granule and P-body assembly

Max Baymiller, Noah S. Helton, Benjamin Dodd, et al.

Selected by 19 May 2025

Mohammed JALLOH

Molecular Biology

TDP-43 directly inhibits rna accumulation in neurites through modulation of rna stability

Charlie Moffatt, Ankita Arora, Katherine F. Vaeth, et al.

Selected by 10 April 2025

Felipe Del Valle Batalla

Cell Biology

Chronic stress antagonizes formation of Stress Granules

Yuichiro Adachi, Allison M. Williams, Masashi Masuda, et al.

Selected by 08 April 2025

Mohammed JALLOH

Cell Biology

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Biochemistry

Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

Nalini R. Rao, Olivia DeGulis, Toshihiro Nomura, et al.

Selected by 11 January 2025

Jawdat Sandakly

Neuroscience