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m6A rna methylation facilitates pre-mrna 3’-end formation and is essential for viability of Toxoplasma gondii

Michael J. Holmes, Leah R. Padgett, Matheus S. Bastos, et al.

AND

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

Dayana C. Farhat, Matthew Bowler, Guillaume Communie, et al.

A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination

Desislava P. Staneva, Roberta Carloni, Tatsiana Auchynnikava, et al.

Discussion

Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes

Itai Antoine Toker, Itamar Lev, Yael Mor, et al.

Discussion

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Discussion

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

Simona Giunta, Solène Hervé, Ryan R. White, et al.

A phospho-regulated ensemble signal motif of α-TAT1 drives dynamic microtubule acetylation

Abhijit Deb Roy, Evan G. Gross, Gayatri S. Pillai, et al.

Discussion

Pseudouridine synthases modify human pre-mrna co-transcriptionally and affect splicing

Discussion

Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence

Man Shun Fu, Livia C. Liporagi-Lopes, Samuel R. dos Santos Júnior, et al.

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Alessandro Stirpe, Nora Guidotti, Sarah Northall, et al.

Recognition of cellular rnas by the S9.6 antibody creates pervasive artefacts when imaging rna:DNA hybrids

John A. Smolka, Lionel A. Sanz, Stella R. Hartono, et al.