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Actin polymerization drives lumen formation in a human epiblast model

Dhiraj Indana, Andrei Zakharov, Youngbin Lim, et al.



Selected by Megane Rayer, Rivka Shapiro

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Jin Hao, et al.



Selected by Monica Tambalo

A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.



Selected by Silvia Becca

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, et al.



Selected by Srivatsava Viswanadha

Multiscale light-sheet organoid imaging framework

Gustavo de Medeiros, Raphael Ortiz, Petr Strnad, et al.



Selected by Osvaldo Contreras

Axis formation in annual killifish: Nodal coordinates morphogenesis in absence of Huluwa prepatterning

Philip B. Abitua, Deniz C. Aksel, Alexander F. Schier



Selected by Girish Kale

Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution

Giuliana Rossi, Sonja Giger, Tania Hübscher, et al.



Selected by Anna Meier

Reconstructing human early embryogenesis in vitro with pluripotent stem cells

Berna Sozen, Victoria Jorgensen, Meng Zhu, et al.



Selected by Martin Estermann

Integer topological defects organize stresses driving tissue morphogenesis

Pau Guillamat, Carles Blanch-Mercader, Karsten Kruse, et al.



Selected by Yamini Ravichandran, Giulia Paci

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.



Selected by Alok Javali

Mechanics regulate human embryonic stem cell self-organization to specify mesoderm

Jonathon M. Muncie, Nadia M.E. Ayad, Johnathon N. Lakins, et al.



Selected by Claire Simon & Sophie Morgani

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