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Species-specific developmental timing is associated with global differences in protein stability in mouse and human

Teresa Rayon, Despina Stamataki, Ruben Perez-Carrasco, et al.

Selected by 16 January 2020

Irepan Salvador-Martinez

Developmental Biology

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.

Selected by 31 December 2019

Zhang-He Goh

Pharmacology and Toxicology

Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism

Joanna Szczepaniak, Peter Holmes, Karthik Rajasekar, et al.

Selected by 22 October 2019

Hannah Behrens

Single molecule mechanics resolves the earliest events in force generation by cardiac myosin

Michael S. Woody, Donald A. Winkelmann, Marco Capitanio, et al.

Selected by 21 August 2019

Alyson Smith

Biophysics

A unified role for membrane-cortex detachment during cell protrusion initiation

Erik S. Welf, Christopher E. Miles, Jaewon Huh, et al.

Selected by 02 August 2019

Martim Dias Gomes

Biophysics

Species-specific oscillation periods of human and mouse segmentation clocks are due to cell autonomous differences in biochemical reaction parameters

Mitsuhiro Matsuda, Hanako Hayashi, Jordi Garcia-Ojalvo, et al.

Selected by 18 June 2019

Irepan Salvador-Martinez

Developmental Biology

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

Sudha Kumari, Michael Mak, Yehchuin Poh, et al.

Selected by 11 June 2019

Tim Fessenden

Immunology

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Selected by 09 May 2019

Pavithran Ravindran

Bioengineering

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Adam K. Glaser, Nicholas P. Reder, Ye Chen, et al.

Selected by 20 March 2019

Tim Fessenden

Bioengineering

Endogenous CRISPR arrays for scalable whole organism lineage tracing

James Cotterell, James Sharpe

Selected by 27 February 2019

Irepan Salvador-Martinez

Bioinformatics

Planar differential growth rates determine the position of folds in complex epithelia

Melda Tozluoğlu, Maria Duda, Natalie J Kirkland, et al.

AND

Buckling of epithelium growing under spherical confinement

Anastasiya Trushko, Ilaria Di Meglio, Aziza Merzouki, et al.

Selected by 23 February 2019

Sundar Naganathan

Biophysics

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Selected by 12 February 2019

David Wright

Biochemistry