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Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

PHYTOMap: Multiplexed single-cell 3D spatial gene expression analysis in plant tissue

Tatsuya Nobori, Marina Oliva, Ryan Lister, et al.

Discussion

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals

Victorya Richardson, Kai Zhang, Nora Engel, et al.

Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation

Amy R. Vandiver, Brittany Pielstick, Timothy Gilpatrick, et al.

Discussion

Local IL-17 orchestrates skin aging

Paloma Solá, Elisabetta Mereu, Júlia Bonjoch, et al.

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, et al.

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, et al.

Lightning Fast and Highly Sensitive Full-Length single-cell sequencing using FLASH-Seq

Vincent Hahaut, Dinko Pavlinic, Cameron Cowan, et al.

Discussion

single-cell transcriptome analysis of embryonic and adult endothelial cells allows to rank the hemogenic potential of post-natal endothelium

Artem Adamov, Yasmin Natalia Serina Secanechia, Christophe Lancrin

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Christian Reuter, Fabian Imdahl, Laura Hauf, et al.

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics

Anna Pryszlak, Tobias Wenzel, Kiley West Seitz, et al.