Search results

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Discussion

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Kenrick A. Waite, Gabrielle Vontz, Stella Y. Lee, et al.

Selected by 05 September 2023

Aniruddha Das

Complete male-to-female sex reversal in XY mice lacking the miR-17∼92 cluster

Alicia Hurtado, Irene Mota-Gómez, Miguel Lao, et al.

Selected by 07 May 2023

Martin Estermann

ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

Aleksandar Bartolome, Julia C. Heiby, Therese Dau, et al.

Selected by 01 May 2023

Aniruddha Das

Discussion

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Selected by 07 April 2023

Benjamin Dominik Maier

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Selected by 22 March 2023

Roberto Amadio

Discussion

Unclearing Microscopy

Ons M’Saad, Michael Shribak, Joerg Bewersdorf

Selected by 02 March 2023

Robert Mahen

Discussion

small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.

Selected by 22 February 2023

Laura Celotto

Genetically encoded multimeric tags for intracellular protein localisation in cryo-EM

Herman KH Fung, Yuki Hayashi, Veijo T Salo, et al.

Selected by 16 January 2023

Martyna Kosno-Vega

Discussion

Diverse logics and grammar encode notochord enhancers

Benjamin P Song, Michelle F Ragsac, Krissie Tellez, et al.

Selected by 21 August 2022

Andrew Montequin

Multifunctional fluorophores for live-cell imaging and affinity capture of proteins

Pratik Kumar, Jason D. Vevea, Edwin R. Chapman, et al.

Selected by 19 August 2022

Zhang-He Goh

Discussion