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A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

Erdem D. Tabdanov, Nelson J. Rodríguez-Merced, Alexander X. Cartagena-Rivera, et al.

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, et al.

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Andrew Wishart, Yifan Peng, Sydney Conner, et al.

The enteric nervous system of the human and mouse colon at a single-cell resolution

Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, et al.

Axon-like protrusions promote small cell lung cancer migration and metastasis

Dian Yang, Fangfei Qu, Hongchen Cai, et al.

Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

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Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Cyp26b1 is required for proper airway epithelial differentiation during lung development

Edward Daniel, Gabrielle I. Sutton, Yadanar Htike, et al.

Single Cell Analysis Reveals Immune Cell-Adipocyte Crosstalk Regulating the Transcription of Thermogenic Adipocytes

Prashant Rajbhandari, Douglas Arneson, An-Chieh Feng, et al.

3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK

Anna V. Taubenberger, Salvatore Girardo, Nicole Träber, et al.

Myc instructs and maintains pancreatic adenocarcinoma phenotype

Nicole M Sodir, Roderik M Kortlever, Valentin JA Barthet, et al.