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Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays

Claire Simonneau, Martina Duschmalé, Alina Gavrilov, et al.

Selected by 20 February 2021

Kristina Kuhbandner

Cell Biology

The Design, Synthesis, and Evaluation of Hypoxia-Activated Prodrugs of the KDAC Inhibitor Panobinostat

Ewen Calder, Anna Skwarska, Deborah Sneddon, et al.

Selected by 01 February 2021

Zhang-He Goh

Pharmacology and Toxicology

Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.

Selected by 27 November 2020

Alexander Ward, Osvaldo Contreras

Bioengineering

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

Fani Pantouli, Travis W. Grim, Cullen L. Schmid, et al.

Selected by 26 November 2020

Nándor Lipták

Animal Behavior and Cognition

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

Charlotte M. de Winde, Samantha L. George, Abbey B. Arp, et al.

Selected by 19 August 2020

Ankita Jha

Cell Biology

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by 11 August 2020

Osvaldo Contreras, Alexander Ward

Cell Biology

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.

Selected by 14 July 2020

Louise Fraser

Immunology

Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model

Kristina M. Bigelow, Rokeya Tasneen, Yong S. Chang, et al.

Selected by 01 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration

Rasha Rezk, Bill Zong Jia, Astrid Wendler, et al.

Selected by 17 June 2020

Mariana De Niz

Cancer Biology

Transplantation of Muscle Stem Cell Mitochondria Rejuvenates the Bioenergetic Function of Dystrophic Muscle

Mahir Mohiuddin, Jeongmoon J. Choi, et al.

Selected by 08 June 2020

Andrea Irazoki

Cell Biology

Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients

Jessica Furner-Pardoe, Blessing O Anonye, Ricky Cain, et al.

AND

The safety profile of Bald’s eyesalve for the treatment of bacterial infections

Blessing O Anonye, Valentine Nweke, Jessica Furner-Pardoe, et al.

Selected by 26 May 2020

Snehal Kadam

Microbiology

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani B. Ho, et al.

Selected by 06 May 2020

Zhang-He Goh

Synthetic Biology