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Human cardiac fibrosis-on-a-chip model recapitulates disease hallmarks and can serve as a platform for drug screening

Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, et al.

Selected by 24 June 2019

Hiroyoshi Y. Tanaka

Bioengineering

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

Sudha Kumari, Michael Mak, Yehchuin Poh, et al.

Selected by 11 June 2019

Tim Fessenden

Immunology

Distinct RhoGEFs activate apical and junctional actomyosin contractility under control of G proteins during epithelial morphogenesis

Alain Garcia De Las Bayonas, Jean-Marc Philippe, Annemarie C. Lellouch, et al.

Selected by 09 April 2019

Ivana Viktorinová

Developmental Biology

Microtubules stabilize intercellular contractile force transmission during tissue folding

Selected by 20 February 2019

Ivana Viktorinová

Cell Biology

Force inference predicts local and tissue-scale stress patterns in epithelia

Weiyuan Kong, Olivier Loison, Pruthvi Chavadimane Shivakumar, et al.

Selected by 17 January 2019

Sundar Naganathan

Biophysics

A non-canonical arm of UPRER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Selected by 07 January 2019

Sandra Franco Iborra

Cell Biology

A non-canonical arm of UPRER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Selected by 17 December 2018

Sandra Malmgren Hill

Cell Biology

Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma.

Andrea Palamidessi, Chiara Malinverno, Emanuela FRITTOLI, et al.

Selected by 15 November 2018

Tim Fessenden

Cell Biology

Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry in vivo

Elena Scarpa, Cedric Finet, Guy Blanchard, et al.

Selected by 05 November 2018

Ivana Viktorinová

Cell Biology

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient

Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, et al.

Selected by 05 November 2018

Tessa Sinnige

Biochemistry

Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo.

Jonathan B Michaux, Francois B Robin, William M McFadden, et al.

Selected by 02 August 2018

Sundar Naganathan

Cell Biology

Mechanosensitive binding of p120-Catenin at cell junctions regulates E-Cadherin turnover and epithelial viscoelasticity

K. Venkatesan Iyer, Romina Piscitello-Gómez, Frank Jülicher, et al.

Selected by 23 July 2018

Ivana Viktorinová

Developmental Biology