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Disrupting a Convergent Acetylation Circuit Collapses Leukemic Identity Across AML Subtypes

Anagha Deshpande, Cho-Ying Chiang, Marlenne Perales, et al.

Selected by 07 September 2026

Zoha Sadaqat

Discussion

Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma

Rebecca Mancusi, Eva Tatlock, Kiarash Shamardani, et al.

Selected by 13 August 2026

CRM UoE Journal Club

Discussion

BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses

Alexander O. D. Gulka, Kihoon A. Kang, Ziben Zhou, et al.

Selected by 08 August 2026

Dina Kabbara

Epigenome editing of human hematopoietic stem cells enables sustained and reversible thrombosis prevention

Tianyi Ye, Wanying Xu, Maria N. Barrachina, et al.

Selected by 06 August 2026

Beth Chopak

Discussion

A pre-rRNA positive feedback loop drives malignant ribosome biogenesis

Emilie L. Alard, Martin Dodel, Shannon N. Russell, et al.

Selected by 02 August 2026

Vaishali Grewal

Minimal essential requirements for neural tube self-organisation

Hannah T. Stuart, Elena Costantini, Jingkui Wang, et al.

Selected by 27 July 2026

Benjamin Swedlund

Discussion

Circadian Clock Programming of Anticipatory Antiviral Immunity Gates Enteric Virus Infection Susceptibility

Temitope O. Oshinowo, Robert W. Maples, Mikal A. Woods Acevedo, et al.

Selected by 12 June 2026

Owen Ang

Evolutionary landscapes of zygotic genome activation across animals

Israel Campo-Bes, Federica Mantica, Jon Permanyer, et al.

Selected by 26 May 2026

Panagiotis Giannios

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

Jethro Lundie-Brown, Rosalind Drummond, John-Poul Ng-Blichfeldt, et al.

Selected by 21 May 2026

Reinier Prosee, Jethro Lundie-Brown

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Selected by 19 May 2026

María Mariner-Faulí

Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis

Emma Carley, Sandra Sandria, Xueyan Peng, et al.

Selected by 13 May 2026

Beth Chopak

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

Quentin A. Thomas, Liyang Wu, Emma Lesage, et al.

Selected by 01 April 2026

Élise Jeanne Pouponnot, Pierre Caron

Discussion