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SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.



Selected by Zhang-He Goh

Proteolysis-free cell migration through crowded environments via mechanical worrying

Meghan K. Driscoll, Erik S. Welf, Andrew Weems, et al.



Selected by Jade Chan

Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, et al.



Selected by Sagar Varankar

Deep Learning Enables Individual Xenograft Cell Classification in Histological Images by Analysis of Contextual Features

Quentin Juppet, Fabio De Martino, Martin Weigert, et al.



Selected by Mariana De Niz

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Andrew Wishart, Yifan Peng, Sydney Conner, et al.



Selected by Vassilis Papalazarou, Anh Hoang Le

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.



Selected by Jonny Coates

A unified role for membrane-cortex detachment during cell protrusion initiation

Erik S. Welf, Christopher E. Miles, Jaewon Huh, et al.



Selected by Martim Dias Gomes

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

Erin N. Howe, Miranda D. Burnette, Melanie E. Justice, et al.



Selected by Beverley Wilson

Pulmonary natural killer cells control neutrophil intravascular motility and response to acute inflammation

J. Secklehner, K. De Filippo, J. B. G. Mackey, et al.



Selected by Jonny Coates

Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics

Emily Clement, Ikrame Lazar, Camille Attané, et al.



Selected by Hannah Brunsdon

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, et al.



Selected by Yasmin Lau

Myc instructs and maintains pancreatic adenocarcinoma phenotype

Nicole M Sodir, Roderik M Kortlever, Valentin JA Barthet, et al.



Selected by William Hill
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