Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
Pierre Caron
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
Jennifer Ann Black
SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species
Selected by
Zhang-He Goh
A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion
Selected by
Benjamin Dominik Maier
Functional synapses between small cell lung cancer and glutamatergic neurons
Selected by
Jade Chan
Proteolysis-free cell migration through crowded environments via mechanical worrying
Selected by
Jade Chan
Actin-driven protrusions generate rapid long-range membrane tension propagation in cells
Selected by
Nicolaes Hyun-Kee Min
An Arp2/3-cPLA2-NFκB axis acts as a Cell Shape Sensor to drive Homeostatic Migration of Dendritic Cells
Selected by
Jade Chan
Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration
Selected by
Jade Chan
Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells
Selected by
Ines Jmel-Boyer
ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations
Selected by
Jennifer Ann Black
The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination
Selected by
Holly Smith