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Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

Jeremy A. Hollis, Jason A. Stonick, Irini Topalidou, et al.

Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes

Aleksandra Ferenc-Mrozek, Maria Winiewska-Szajewska, Hanna Nieznańska, et al.

Discussion

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, Maria Miranda, Fangcong Dong, et al.

Discussion

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Discussion

DNA Specimen Preservation using DESS and DNA Extraction in Museum Collections: A Case Study Report

Eri Ogiso-Tanaka, Daisuke Shimada, Akito Ogawa, et al.

Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms

Keirah E. Bartlett, Adam Westhorpe, Mark C. Wilkinson, et al.

Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling

Haley N. Bridge, Chase L. Radziej, Amy M. Weeks

Discussion

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation

Rudolf Pisa, Tom A. Rapoport

Discussion

HAK-actin, U-ExM-compatible probe to image the actin cytoskeleton

Olivier Mercey, Luc Reymond, Florent Lemaître, et al.

Tandem duplication of serpin genes yields functional variation and snake venom inhibitors

Meilyn S. Ward, Matthew L. Holding, Laura M. Haynes, et al.

Discussion

A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

Thomas Moss, Alexandra Wooldredge, Koustav Bhakta, et al.

Discussion