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Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Kerstin Klinkert, Nicolas Levernier, Peter Gross, et al.

AND

Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Sachin Kotak, Sukriti Kapoor

Selected by 09 September 2018

Giuliana Clemente

Cell Biology

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike B Barnkob, Hector Barbosa, et al.

Selected by 08 August 2018

Tim Fessenden

Genomics

Moving beyond P values: Everyday data analysis with estimation plots

Joses Ho, Tayfun Tumkaya, Sameer Aryal, et al.

Selected by 01 August 2018

Dey Lab

Scientific Communication and Education

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

Jessica Messier, Hongmei Chen, Zhao-Lin Cai, et al.

AND

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

Mathias Mahn, Lihi Gibor, Katayun Cohen-Kashi Malina, et al.

Selected by 22 July 2018

Mahesh Karnani

Neuroscience

A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states.

Sandeep Krishna, Sunil Laxman

Selected by 09 July 2018

Lauren Neves

Systems Biology

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

Gist H. Farr III, Kimia Imani, Darren Pouv, et al.

Selected by 03 July 2018

Hannah Brunsdon

Genetics

Large-scale, quantitative protein assays on a high-throughput DNA sequencing chip

Curtis J Layton, Peter L McMahon, William J Greenleaf

Selected by 26 June 2018

Samantha Seah

Molecular Biology

Molecular dynamics simulations disclose early stages of the photo-activation of cryptochrome 4

Daniel R. Kattnig, Claus Nielsen, Ilia A. Solov'yov

Selected by 04 June 2018

Miriam Liedvogel

Biophysics

Genetically regulated human NODAL splice variants are differentially post-transcriptionally processed and functionally distinct

Scott D Findlay, Olena Bilyk, Kiefer Lypka, et al.

Selected by 03 April 2018

Pierre Osteil

Developmental Biology

Directed evolution of TurboID for efficient proximity labeling in living cells and organisms

Tess C Branon, Justin A Bosch, Ariana D Sanchez, et al.

Selected by 22 March 2018

Ralph Böttcher

Cell Biology

Comprehensive characterization of transcript diversity at the human NODAL locus

Scott D Findlay, Lynne-Marie Postovit

Selected by 19 February 2018

Christian Ramos

Molecular Biology