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Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.

Enveloped viruses show increased propensity to cross-species transmission and zoonosis

Ana Valero-Rello, Rafael Sanjuán

Synthetic memory circuits for programmable cell reconfiguration in plants

James P B Lloyd, Florence Ly, Patrick Gong, et al.

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Synthetic genetic circuits enable reprogramming of plant roots

Jennifer A. N. Brophy, Katie J. Magallon, Kiril Kniazev, et al.

RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

Jingwen Guan, Agnès Oromí-Bosch, Senén D. Mendoza, et al.

A cell fate decision map reveals abundant direct neurogenesis in the human developing neocortex

Laure Coquand, Anne-Sophie Macé, Sarah Farcy, et al.

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Reversible bacteriophage resistance by shedding the bacterial cell wall

Veronique Ongenae, Adam Sidi Mabrouk, Marjolein Crooijmans, et al.

Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels

Maria Elena De Obaldia, Takeshi Morita, Laura C. Dedmon, et al.

NLR immune receptor-nanobody fusions confer plant disease resistance

Jiorgos Kourelis, Clémence Marchal, Sophien Kamoun

Nuclear soluble cGAS senses DNA virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, et al.

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

Benjamin J. Tuck, Taxiarchis Katsinelos, Lauren V. C. Miller, et al.

STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

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The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.