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Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Molecular Biology

AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

Souvik Ghosh, Joao C Guimaraes, Manuela Lanzafame, et al.

Selected by 05 May 2019

Lorenzo Lafranchi

Cancer Biology

Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff

Rossana S Colon-Thillet, Emily S Hsieh, Laura Graf, et al.

Selected by 13 March 2019

Connor Rosen

Immunology

HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly

C. Favard, J. Chojnacki, P. Merida, et al.

Selected by 11 March 2019

Amberley Stephens

Cell Biology

Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs

Lucas T Graybuck, Adriana Sedeño-Cortés, Thuc Nghi Nguyen, et al.

Selected by 27 February 2019

Jesus Victorino

Neuroscience

Functional characterization of Arabidopsis ARGONAUTE 3 in reproductive tissue

Pauline E Jullien, Stefan Grob, Antonin Marchais, et al.

Selected by 21 January 2019

Chandra Shekhar Misra

Developmental Biology

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Diego Gauto, Leandro Estrozi, Charles Schwieters, et al.

Selected by 05 January 2019

Reid Alderson

Biophysics

Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Sonali Chaturvedi, Marie Wolf, Noam Vardi, et al.

Selected by 03 January 2019

Pavithran Ravindran

Biochemistry

Robust Antibacterial Activity of Tungsten Oxide (WO3-X) Nanodots

Guangxin Duan, Lu Chen, Zhifeng Jing, et al.

Selected by 21 December 2018

Zhang-He Goh

Pharmacology and Toxicology

RNase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs

James M Burke, Stephanie L Moon, Evan T Lester, et al.

Selected by 21 December 2018

Connor Rosen

Immunology

Multi-color single molecule imaging uncovers extensive heterogeneity in mRNA decoding

Sanne Boersma, Deepak Khuperkar, Bram M.P. Verhagen, et al.

AND

Live-cell single RNA imaging reveals bursts of translational frameshifting

Kenneth R Lyon Jr, Luis U Aguilera, Tatsuya Morisaki, et al.

Selected by 18 December 2018

Nicola Stevenson

Biochemistry