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Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin

Kathryn E. Woods, Sana Akhter, Blanca Rodriguez, et al.

Selected by 22 May 2024

UofA IMB565 et al.

Microbiology

State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold

James P. Roney, Sergey Ovchinnikov

Selected by 13 April 2022

Kieran Didi

Bioinformatics

Architecture of the AP2:clathrin coat on the membranes of clathrin-coated vesicles

Oleksiy Kovtun, Veronica Kane Dickson, Bernard T. Kelly, et al.

AND

The Structures of Natively Assembled Clathrin Coated Vesicles

Mohammadreza Paraan, Joshua Mendez, Savanna Sharum, et al.

Selected by 24 February 2020

Stephen Royle

Cell Biology

Direct ETTIN-auxin interaction controls chromatin state in gynoecium development

André Kuhn, Sigurd Ramans Harborough, Heather M. McLaughlin, et al.

Selected by 18 December 2019

Martin Balcerowicz

Plant Biology

Shake-it-off: A simple ultrasonic cryo-EM specimen preparation device

John L. Rubinstein, Hui Guo, Zev A. Ripstein, et al.

Selected by 21 May 2019

David Wright

Biochemistry

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Biochemistry

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

Sherine E. Thomas, Andrew J. Whitehouse, Karen Brown, et al.

Selected by 05 March 2019

Yasmin Lau

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Diego Gauto, Leandro Estrozi, Charles Schwieters, et al.

Selected by 05 January 2019

Reid Alderson

Biophysics

Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM

Ricardo Righetto, Nikhil Biyani, Julia Kowal, et al.

Selected by 17 December 2018

David Wright

Biochemistry

The structural basis for release factor activation during translation termination revealed by time-resolved cryogenic electron microscopy

Ziao Fu, Gabriele Indrisiunaite, Sandip Kaledhonkar, et al.

Selected by 11 December 2018

David Wright

Biochemistry

Dynamics and interactions of ADP/ATP transporter AAC3 in DPC detergent are not functionally relevant

Vilius Kurauskas, Audrey Hessel, François Dehez, et al.

AND

Major concerns with the integrity of the mitochondrial ADP/ATP carrier in dodecyl-phosphocholine used for solution NMR studies

Martin S. King, Paul G. Crichton, Jonathan J. Ruprecht, et al.

Selected by 23 July 2018

Reid Alderson

Biophysics

Structural Basis of Tubulin Recruitment and Assembly by Tumor Overexpressed Gene (TOG) domain array Microtubule Polymerases

Stanley Nithiananatham, Brian Cook, Fred Chang, et al.

AND

Roles for tubulin recruitment and self-organization by TOG domain arrays in Microtubule plus-end tracking and polymerase

Brian Cook, Fred Chang, Ignacio Flor-Parra, et al.

Selected by 25 June 2018

Ben Craske, Gaetan Dias Mirandela, Thibault Legal and Toni McHugh

Biochemistry