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Filtered by systems biology category

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan



Selected by Connor Rosen

Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.



Selected by Alexander Ward, Osvaldo Contreras

Generative modeling of single-cell population time series for inferring cell differentiation landscapes

Grace H.T. Yeo, Sachit D. Saksena, David K. Gifford



Selected by Yen-Chung Chen

High-throughput discovery and characterization of human transcriptional effectors

Josh Tycko, Nicole DelRosso, Gaelen T. Hess, et al.



Selected by Clarice Hong

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.



Selected by Osvaldo Contreras, Alexander Ward

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.



Selected by Pavithran Ravindran

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Collin R Diedrich, Tara Rutledge, Pauline Maiello, et al.



Selected by Louise Fraser

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, et al.



Selected by Robert Mahen
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