LINC complex alterations are a hallmark of sporadic and familial ALS/FTD
Selected by
03 June 2024
Megane Rayer et al.
Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis
Selected by
16 April 2024
Julio Molina Pineda
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4
Selected by
22 October 2023
Aniruddha Das
VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity
Selected by
10 February 2023
Kritika Mehta
Motion of single molecular tethers reveals dynamic subdomains at ER-mitochondria contact sites
Selected by
06 November 2022
Holly Smith
A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis
Selected by
09 April 2021
Utrecht Protein Folding and Assembly
Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates
Selected by
11 March 2021
Kristina Kuhbandner
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Selected by
05 February 2021
Sree Rama Chaitanya, Giuseppina D'Alessandro
Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
Selected by
10 September 2020
Kristina Kuhbandner
amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
Selected by
01 August 2020
Kristina Kuhbandner
FUS gene is dual-coding with both proteins united in FUS-mediated toxicity
Selected by
12 May 2020
Madhuja Samaddar
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
Selected by
30 August 2019
Madhuja Samaddar