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Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate

This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.

 



List by Virginia Savy, Martin Estermann

Synapses drive local mitochondrial ATP synthesis to fuel plasticity

Ilika Ghosh, Ruolin Fan, Monil Shah, et al.

Selected by 02 May 2025

Felipe Del Valle Batalla

Neuroscience

April in preprints – the CellBio edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics

 



List by Vibha SINGH et al.

3D mechanical confinement directs muscle stem cell fate and function

GaYoung Park, Josh A. Grey, Foteini Mourkioti, et al.

Selected by 30 April 2025

Justin Gutkowski

Bioengineering

Heart Scar-In-A-Dish: Tissue Culture Platform to Study Myocardial Infarct Healing In Vitro

MJ Potter, JD Heywood, SJ Coeyman, et al.

Selected by 28 April 2025

Theodora Stougiannou

Bioengineering

Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion

Jessica Wagner, Konstantina Feller, Nicole Schrenke, et al.

Selected by 25 April 2025

Vibha SINGH

Cancer Biology

Fibroblast growth factor 21 regulates neuromuscular junction innervation through HDAC4 in denervation-induced skeletal muscle atrophy

Lirong Zheng, Takashi Sasaki, Liyang Ni, et al.

Selected by 25 April 2025

Jórdan Sampar

Neuroscience

STEAMBOAT: Attention-based multiscale delineation of cellular interactions in tissues

Shaoheng Liang, Junjie Tang, Guanghan Wang, et al.

Selected by 25 April 2025

Benjamin Dominik Maier

Bioinformatics

Wnt signaling restores evolutionary loss of regenerative potential in Hydra

Sergio E. Campos, Sahar Naziri, Jackson Crane, et al.

Selected by 23 April 2025

Ruoheng Li

Developmental Biology

An experimental test of the influence of microbial manipulation on sugar kelp (Saccharina latissima) supports the core influences host function hypothesis

Jungsoo Park, Evan Kohn, Siobhan Schenk, et al.

Selected by 15 April 2025

Jasmine Talevi

Ecology

Unexpected mechanisms of sex-specific memory vulnerabilities to acute traumatic stress

Rachael E. Hokenson, Kiara L. Rodríguez-Acevedo, Yuncai Chen, et al.

Selected by 11 April 2025

Jimeng Li

Neuroscience

Tooth development in frogs: Implications for the re-evolution of lost mandibular teeth and the origin of a morphological innovation

Daniel J. Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, et al.

Selected by 11 April 2025

Ryan Harrison

Developmental Biology