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A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Discussion

Upregulation and cell specificity of C₄ genes are derived from ancestral C₃ gene regulatory networks

Pallavi Singh, Sean R. Stevenson, Ivan Reyna-Llorens, et al.

Discussion

Mutation bias shapes gene evolution in Arabidopsis thaliana

J. Grey Monroe, Thanvi Srikant, Pablo Carbonell-Bejerano, et al.

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Discussion

Gain of gene regulatory network interconnectivity at the origin of vertebrates

Alejandro Gil-Gálvez, Sandra Jiménez-Gancedo, Rafael D. Acemel, et al.

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

Akihiko Sakashita, So Maezawa, Kris G. Alavattam, et al.

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

AND

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Discussion

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8⁺ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.

Discussion

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Discussion