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MechanoMaST – a multimodal pipeline for spatially registering mechanical and transcriptomic tissue data

Linda Decker, Dmitrii Olisov, Nikolai Schleußner, et al.

AND

Paired-surface spatial mechanomics links tissue stiffness maps to spatial transcriptomics

Huan Ting Ong, Yuting Lou, Jake Turley, et al.

Choreographed morphogenetic events underlie early foregut development in the mouse embryo

Jenny Kretzschmar, Guillermo Serrano Nájera, Sonia Agüera-Gonzalez, et al.

Disrupting a Convergent Acetylation Circuit Collapses Leukemic Identity Across AML Subtypes

Anagha Deshpande, Cho-Ying Chiang, Marlenne Perales, et al.

Discussion

The Aorta-Gonad-Mesonephros niche shapes the functions of yolk sac-derived macrophages involved in hematopoietic stem and progenitor cell generation ex vivo

Rebecca L. Belmonte, Marianna Romano, Anna Popravko, et al.

Hydrostatic pressure shapes and canalizes semicircular canal morphology to ensure vestibular function

Jiacheng Wang, Kira L. Heikes, Yufei Wu, et al.

Discussion

Structure of chlorophyll synthase in complex with the LHC-like protein HliD

Dmitry Shvarev, Anna Wysocka, Felix S. Morey-Burrows, et al.

Neuronal calcium sensors emerge as novel adenylyl cyclase 8 regulators

Basavraj Khanppnavar, Roberta Florea, Dina Schuster, et al.

Discussion

Disordered protein COSA-2 maintains crossover-specific repair compartments to ensure meiotic crossover maturation

Celja J. Uebel, Dahlia Y. Deng, Yumi Kim, et al.

Discussion

CENP-B binds hairpin motifs in chromosome arms influencing gene expression

Lillian Wu, Karen A Lane, Reyhan Muhammad, et al.

Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate

Ayami Takaochi, Kota Abe, Yuki Sugiura, et al.

Discussion

A Cell Size-Dependent Competition Between Geometry and Polarity Governs Nuclear and Spindle positioning in Early Embryos

Aude Nommick, Macy Baboch, Celia Municio-Diaz, et al.

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

Amélia Sarmento, Tommy Regen, Daniela Ferro, et al.

Discussion