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The mutational landscape of human somatic and germline cells

Luiza Moore, Alex Cagan, Tim Coorens, et al.

Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors

Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, et al.

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

Double Emulsion Picoreactors for High-Throughput Single-Cell Encapsulation and Phenotyping via FACS

Kara K. Brower, Margarita Khariton, Peter H. Suzuki, et al.

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Lineage recording reveals dynamics of cerebral organoid regionalization

Zhisong He, Tobias Gerber, Ashley Maynard, et al.

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

LINE elements are a reservoir of regulatory potential in mammalian genomes

Maša Roller, Ericca Stamper, Diego Villar, et al.

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.

Gain of gene regulatory network interconnectivity at the origin of vertebrates

Alejandro Gil-Gálvez, Sandra Jiménez-Gancedo, Rafael D. Acemel, et al.