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cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Discussion

Nuclear soluble cGAS senses DNA virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, et al.

STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

AND

The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.

Discussion

A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2

Aurora Kraus, Elisa Casadei, Mar Huertas, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Discussion

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque, et al.

Discussion

Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

Jiwen Li, Lin Pan, Marlesa I. Godoy, et al.

Discussion

Conflicts with diarrheal pathogens trigger rapid evolution of an intestinal signaling axis

Clayton M. Carey, Sarah E. Apple, Zoё A. Hilbert, et al.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, et al.

The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces

Yingxue Wang, Weijiao Zhang, Matthew Jefferson, et al.

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Discussion