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Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling

Haley N. Bridge, Chase L. Radziej, Amy M. Weeks

Selected by 31 December 2025

Zhang-He Goh

Biochemistry

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S.C. Gravett, et al.

Selected by 31 December 2025

Vibha SINGH

Cell Biology

PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Selected by 29 December 2025

Vibha SINGH

Cell Biology

Junctional Heterogeneity Shapes Epithelial Morphospace

Anubhav Prakash, Raman Kaushik, Nishant Singh, et al.

Selected by 25 December 2025

Bhaval Parmar

Developmental Biology

Mitochondrial Fatty Acid Oxidation is Stimulated by Red light Irradiation

Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Mauricio S. Baptista, et al.

Selected by 19 December 2025

Rickson Ribeiro, Marcus Oliveira

Biochemistry

Loss of MGST1 during fibroblast differentiation enhances vulnerability to oxidative stress in human heart failure

Mohamad Youness, Onne A.H.O. Ronda, Ankit Pradhan, et al.

Selected by 15 December 2025

Jeny Jose

Immunology

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Wei Zheng, Igor Siwanowicz, et al.

Selected by 12 December 2025

Muhammed Sinan Malik

Neuroscience

Microbial Feast or Famine: dietary carbohydrate composition and gut microbiota metabolic function

Blake Dirks, Alex E. Mohr, Karen D. Corbin, et al.

Selected by 11 December 2025

Jasmine Talevi

Microbiology

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Selected by 09 December 2025

Inês Caiado

Immunology

Dosage-sensitive RBFOX2 autoregulation promotes cardiomyocyte differentiation by maturing the transcriptome

Mengmeng Huang, Feria A. Ladha, Yunxia Wang, et al.

Selected by 06 December 2025

Theodora Stougiannou

Developmental Biology

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Selected by 02 December 2025

Siddharth Singh

Evolutionary Biology