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Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

Amélia Sarmento, Tommy Regen, Daniela Ferro, et al.

Discussion

Prenatal Stress Differentially Shapes Adult Behavior in Male and Female Offspring

Erbo Dong, Alison Chu, Tamar Gur, et al.

Discussion

Experimental evolution of cellular miniaturization reveals a putative mechanism for cell size evolution

Garoña Ana, Lemos Victoria Morgane, Giometto Andrea, et al.

No global collapse of food webs across the Permian–Triassic Mass Extinction

Baran Karapunar, Tanya Strydom, Andrew P. Beckerman, et al.

Discussion

Science should be machine-readable

A. Sina Booeshaghi, Laura Luebbert, Lior Pachter

Discussion

UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism

Phong T. Nguyen, Zheng Wu, Dohun Kim, et al.

Exogenous Amyloid Sequences: Their Role in Amyloid-Beta Heterotypic Aggregation

Jofre Seira Curto, Sandra Villegas, Maria Rosario Fernandez, et al.

Discussion

Human Assembloid model of Emergent Neurotropic Enteroviruses

Christine E. Peters, Jimena Andersen, Min-Yin Li, et al.

Discussion

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Discussion

A thirty-year trend of increasing clinical orientation at the National Institutes of Health

Brad L. Busse, James M. Tucker, Summer E. Allen, et al.

AND

Prediction of transformative breakthroughs in biomedical research

Matthew T. Davis, Brad L. Busse, Salsabil Arabi, et al.