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Mutational signatures are jointly shaped by DNA damage and repair

Nadezda V Volkova, Bettina Meier, Víctor González-Huici, et al.

Selected by 24 February 2020

Kerryn Elliott

Cancer Biology

Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Chiara Rezzoagli, Martina Archetti, Michael Baumgartner, et al.

Selected by 10 December 2019

Zhang-He Goh

Pharmacology and Toxicology

A conserved ATG2-GABARAP interaction is critical for phagophore closure

Mihaela Bozic, Luuk van den Bekerom, Beth A. Milne, et al.

Selected by 12 September 2019

Mila Basic

Cell Biology

Engineering Phage Host-Range and Suppressing Bacterial Resistance Through Phage Tail Fiber mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Synthetic Biology

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Molecular Biology

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker, et al.

Selected by 23 May 2019

Gabriel Aughey

Genetics

Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff

Rossana S Colon-Thillet, Emily S Hsieh, Laura Graf, et al.

Selected by 13 March 2019

Connor Rosen

Immunology

Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry

Stephanie Cara Bishop, Robert Winefield, Asokan Anbanandam, et al.

Selected by 11 March 2019

Zhang-He Goh

Biochemistry

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Selected by 12 February 2019

David Wright

Biochemistry

Structure of a cytochrome-based bacterial nanowire

David J Filman, Stephen F Marino, Joy E Ward, et al.

Selected by 21 December 2018

Amberley Stephens

Microbiology

Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions

Summer B. Thyme, Lindsey M. Pieper, Eric H. Li, et al.

Selected by 20 July 2018

Daniel Grimes

Genetics

Super-Mendelian inheritance mediated by CRISPR/Cas9 in the female mouse germline

Hannah A. Grunwald, Valentino M. Gantz, Gunnar Poplawski, et al.

Selected by 16 July 2018

Rebekah Tillotson

Synthetic Biology