Search results

A direct experimental test of Ohno’s hypothesis

Ljiljana Mihajlovic, Bharat Ravi Iyengar, Florian Baier, et al.

Selected by 04 December 2023

Alejandra Herbert Leffler's Lab

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

Selected by 04 December 2023

Matthew Davies

Discussion

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by 14 November 2023

Audrey Noireterre

Ancient origins of complex neuronal genes

Matthew J. McCoy, Andrew Z. Fire

Selected by 23 October 2023

Preethi Krishnaraj, Chee Kiang Ewe

Discussion

Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Thuy P. Dao, Anitha Rajendran, Sarasi K. K. Galagedera, et al.

Selected by 22 October 2023

Aniruddha Das

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Discussion

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Discussion

PYCR1 Levels Track with Premature and Chronological Skin Aging

Kortessa Sotiropoulou, Saniye Yumlu, Tomoko Hirano, et al.

Selected by 17 August 2023

Preethi Krishnaraj

Discussion

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

Nanami Senoo, Dinesh K. Chinthapalli, Matthew G. Baile, et al.

Selected by 14 July 2023

Barbora Knotkova

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

DNA methylation rates scale with maximum lifespan across mammals

Samuel. J. C. Crofts, Eric Latorre-Crespo, Tamir Chandra

Selected by 13 June 2023

Jennifer Ann Black