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BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by 09 March 2023

Pierre Caron

Cancer Biology

Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing

Mei Hong Liu, Benjamin Costa, Una Choi, et al.

Selected by 28 February 2023

Kerryn Elliott

Alumni

The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

Claudia Carlantoni, Leon Liekfeld, Sandra A. Hemkemeyer, et al.

Selected by 20 February 2023

Andreas van Impel, Sanjay Sunil Kumar

Developmental Biology

Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis

Irene Mota-Gómez, Juan Antonio Rodríguez, Shannon Dupont, et al.

Selected by 13 December 2022

Martin Estermann

Bioinformatics

Motion of single molecular tethers reveals dynamic subdomains at ER-mitochondria contact sites

Christopher J. Obara, Jonathon Nixon-Abell, Andrew S. Moore, et al.

Selected by 06 November 2022

Holly Smith

Cell Biology

A specialized mRNA translation circuit instated in pluripotency presets the competence for cardiogenesis in humans

Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, et al.

Selected by 02 November 2022

Emma Armitage

Gigaxonin is required for intermediate filament transport

Bhuvanasundar Renganathan, James P Zewe, Yuan Cheng, et al.

Selected by 01 November 2022

Suganya Sivagurunathan

Cell Biology

Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

Johanna Lilja, Jasmin Kaivola, James R.W. Conway, et al.

Selected by 23 October 2022

Yvonne Xinyi Lim

Cancer Biology

Diverse logics and grammar encode notochord enhancers

Benjamin P Song, Michelle F Ragsac, Krissie Tellez, et al.

Selected by 21 August 2022

Andrew Montequin

Epistasis between promoter activity and coding mutations shapes gene evolvability

Angel F. Cisneros, Isabelle Gagnon-Arsenault, Alexandre K. Dubé, et al.

Selected by 27 June 2022

Jennifer Ann Black

Evolutionary Biology

A motor-based approach to induce chromosome-specific mis-segregations in human cells

My Anh Truong, Paula Cané-Gasull, Sippe G. de Vries, et al.

AND

Inducing Specific Chromosome Mis-Segregation in Human Cells

Laura Tovini, Sarah C. Johnson, Alexander M. Andersen, et al.

Selected by 12 May 2022

Jana Helsen, Dey Lab

Cell Biology

Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation

Amy R. Vandiver, Brittany Pielstick, Timothy Gilpatrick, et al.

Selected by 29 April 2022

Nate Mullin

Genetics