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Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Molecular Biology

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Molecular Biology

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Selected by 10 April 2023

Benjamin Dominik Maier

Systems Biology

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Selected by 23 March 2023

Saanjbati Adhikari

Biochemistry

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Selected by 22 March 2023

Roberto Amadio

Cell Biology

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by 09 March 2023

Pierre Caron

Cancer Biology

Conserved Chamber-Specific Polyploidy Maintains Heart Function in Drosophila

Archan Chakraborty, Nora G. Peterson, Juliet S. King, et al.

Selected by 03 March 2023

Anastasia Moraiti

Cell Biology

Unclearing Microscopy

Ons M’Saad, Michael Shribak, Joerg Bewersdorf

Selected by 02 March 2023

Robert Mahen

Physiology

Insm1 regulates the development of mTECs and immune tolerance

Wehuai Tao, Yiqiu Wei, Zhihuan Ye, et al.

Selected by 28 February 2023

Marina Schernthanner, Jessica Chevallier

Bioinformatics

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by 16 February 2023

Diego Martínez

Cell Biology

Proteolysis-free cell migration through crowded environments via mechanical worrying

Meghan K. Driscoll, Erik S. Welf, Andrew Weems, et al.

Selected by 05 December 2022

Jade Chan

Cell Biology

Expansion microscopy at one nanometer resolution

Ali H. Shaib, Abed Alrahman Chouaib, Vanessa Imani, et al.

Selected by 24 November 2022

Nadja Hümpfer

Cell Biology