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Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Biochemistry

Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

Nuria Ferrandiz, Laura Downie, Georgina P. Starling, et al.

Selected by 29 May 2021

Leonor Keating

Cell Biology

Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons

Abeer Dagra, Douglas R. Miller, Fatemeh Shaerzadeh, et al.

Selected by 26 May 2021

Emma Wilson

Neuroscience

Asynchronous nuclear cycles in multinucleated Plasmodium falciparum enable rapid proliferation

Severina Klaus, Patrick Binder, Juyeop Kim, et al.

Selected by 24 May 2021

Joao Mello-Vieira

Microbiology

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by 20 May 2021

Eric McGregor

Cell Biology

Selectivity of Protein Interactions along the Aggregation Pathway of α-Synuclein

André D. G. Leitão, Paulina Rudolffi Soto, Alexandre Chappard, et al.

Selected by 15 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

Brain deletion of Serf2 shifts amyloid conformation in a mouse model

E. Stroo, L. Janssen, O. Sin, et al.

Selected by 06 April 2021

Utrecht Protein Folding and Assembly

Molecular Biology

Collagen polarization provides a structural memory for the elongation of epithelial anlage

Hiroko Katsuno-Kambe, Jessica L. Teo, Robert J. Ju, et al.

Selected by 19 March 2021

Ilaria Di Meglio

Cell Biology

Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates

Jack H. Brelstaff, Matthew Mason, Taxiarchis Katsinelos, et al.

Selected by 11 March 2021

Kristina Kuhbandner

Neuroscience

Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays

Claire Simonneau, Martina Duschmalé, Alina Gavrilov, et al.

Selected by 20 February 2021

Kristina Kuhbandner

Cell Biology

Mitotic R-loops direct Aurora B kinase to maintain centromeric cohesion

Erin C. Moran, Limin Liu, Ewelina Zasadzinska, et al.

Selected by 10 February 2021

Jennifer Ann Black

Cell Biology

Antiviral activity of bacterial TIR domains via signaling molecules that trigger cell death

Gal Ofir, Ehud Herbst, Maya Baroz, et al.

Selected by 05 February 2021

Jonny Coates, Connor Rosen

Cell Biology