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Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

A cell fate decision map reveals abundant direct neurogenesis in the human developing neocortex

Laure Coquand, Anne-Sophie Macé, Sarah Farcy, et al.

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, et al.

Microstructured hydrogels to guide self-assembly and function of lung alveolospheres

Claudia Loebel, Aaron I. Weiner, Jeremy B. Katzen, et al.

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, et al.

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, et al.

Multiscale light-sheet organoid imaging framework

Gustavo de Medeiros, Raphael Ortiz, Petr Strnad, et al.

Engineering functional human gastrointestinal organoid tissues using the three primary germ layers separately derived from pluripotent stem cells

Alexandra K. Eicher, Daniel O. Kechele, Nambirajan Sundaram, et al.

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

Kyungtae Lim, Walfred Tang, Dawei Sun, et al.

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

Guillermo Martínez-Ara, Núria Taberner, Mami Takayama, et al.

YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.

Discussion

Axis formation in annual killifish: Nodal coordinates morphogenesis in absence of Huluwa prepatterning

Philip B. Abitua, Deniz C. Aksel, Alexander F. Schier