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Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes

Aleksandra Ferenc-Mrozek, Maria Winiewska-Szajewska, Hanna Nieznańska, et al.

Selected by 06 April 2026

Joao Gabriel, Marcus Oliveira

A potential anti-amyloidogenic therapy for type 2 diabetes based on the QBP1 peptide

María M. Tejero-Ojeda, Ada Bernaus Vives, Michal Wojciechowski, et al.

Selected by 01 April 2026

Joao Gabriel, Marcus Oliveira

Discussion

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

Quentin A. Thomas, Liyang Wu, Emma Lesage, et al.

Selected by 01 April 2026

Élise Jeanne Pouponnot, Pierre Caron

Discussion

Cell-intrinsic compliance mechanism enables release of tensile stress to prevent tissue rupture

Chun Wai Kwan, Shunta Sakaguchi, Michiko Takeda, et al.

Selected by 04 March 2026

Ruoheng Li

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Selected by 11 February 2026

Isabel Paine

Discussion

Loss of MGST1 during fibroblast differentiation enhances vulnerability to oxidative stress in human heart failure

Mohamad Youness, Onne A.H.O. Ronda, Ankit Pradhan, et al.

Selected by 15 December 2025

Jeny Jose

Discussion

ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion

Daniel A. Reed, Anna E. Howell, Nadia Kuepper, et al.

Selected by 27 November 2025

Sharvari Pitke

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, et al.

Selected by 26 November 2025

Hannah Pletcher

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Selected by 11 November 2025

Charis Qi

Discussion

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Discussion

Stress granules formed during different RNA virus infections show remarkable plasticity and substantial virus-specific differences in their formation and composition

Reto M. Lang, Silvio Steiner, Jenna Kelly, et al.

Selected by 03 November 2025

Mohammed JALLOH

Discussion