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The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by 14 November 2023

Audrey Noireterre

Cancer Biology

LincRNAs enable germ cells differentiation by promoting PUF proteins condensation

Roni Falk, Noa Gilad, Hanna Achache, et al.

Selected by 30 October 2023

Umutcan Kaan Bozan et al.

Developmental Biology

short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Thuy P. Dao, Anitha Rajendran, sarasi K. K. Galagedera, et al.

Selected by 22 October 2023

Aniruddha Das

Biochemistry

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich sohn

Biochemistry

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP signaling

Luyang Xiong, Irina Zhevlakova, Xiaoxia Z. West, et al.

Selected by 14 September 2023

Marina schernthanner

Immunology

Mechano-dependent sorbitol accumulation supports biomolecular condensate

stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.

Selected by 07 September 2023

Teodora Piskova

Cell Biology

CRIsPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv s. Garje, swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Cell Biology

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Kenrick A. Waite, Gabrielle Vontz, stella Y. Lee, et al.

Selected by 05 September 2023

Aniruddha Das

Biochemistry

subchronic alteration of vestibular hair cells in mice: implications for multisensory gaze stabilization

Louise schenberg, Aïda Palou, François simon, et al.

Selected by 13 July 2023

samantha Davis

Neuroscience

Mitochondrial citrate carrier sLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, et al.

Selected by 12 July 2023

Chee Kiang Ewe, Preethi Krishnaraj

Developmental Biology

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Molecular Biology

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. schreuder, R.s. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Molecular Biology