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A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis

McAlary L., Shephard V.K., Wright G.S.A., et al.

Selected by 09 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Biochemistry

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.

Selected by 27 January 2021

Fabio Liberante

Genomics

GAK and PRKCD are positive regulators of PRKN-independent mitophagy

Michael J. Munson, Benan J. Mathai, Laura Trachsel, et al.

Selected by 19 January 2021

Kirsty Hooper

Cell Biology

Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging

Francesco Rota Sperti, Thibaut Charbonnier, Pauline Lejault, et al.

Selected by 11 January 2021

Jennifer Ann Black

Biophysics

EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break

Teressa Paulsen, Pumoli Malapati, Rebeka Eki, et al.

Selected by 05 January 2021

Sree Rama Chaitanya

Cancer Biology

Design of smart antibody mimetics with photosensitive switches

Lian He, Peng Tan, Yun Huang, et al.

Selected by 30 December 2020

Zhang-He Goh

Synthetic Biology

Force requirements of endocytic vesicle formation

Marc Abella, Lynnel Andruck, Gabriele Malengo, et al.

Selected by 18 December 2020

Mariana De Niz

Biophysics

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan

Selected by 09 December 2020

Connor Rosen

Immunology

A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2

Aurora Kraus, Elisa Casadei, Mar Huertas, et al.

Selected by 04 December 2020

Mariana De Niz

Immunology

Nuclear stiffness decreases with disruption of the extracellular matrix in living tissues

Kaitlin P. McCreery, Xin Xu, Adrienne K. Scott, et al.

Selected by 02 December 2020

Mariana De Niz

Cell Biology

Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.

Selected by 27 November 2020

Alexander Ward, Osvaldo Contreras

Bioengineering