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Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Adam K. Glaser, Nicholas P. Reder, Ye Chen, et al.

Human Handedness: Genetics, Microtubules, Neuropsychiatric Diseases and Brain Language Areas

Akira Wiberg, Gwenaelle Douaud, Michael Ng, et al.

Dynamic Aha1 Co-Chaperone Binding to Human Hsp90

Javier Oroz, Laura J Blair, Markus Zweckstetter

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Microtubules Gate tau Condensation to Spatially Regulate Microtubule Functions

Ruensern Tan, Aileen J. Lam, Tracy Tan, et al.

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Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

Valerie Siahaan, Jochen Krattenmacher, Amayra Hernandez-Vega, et al.

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient

Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, et al.

millepattes micropeptides are an ancient developmental switch required for embryonic patterning

Suparna Ray, Miriam I Rosenberg, Hélène Chanut-Delalande, et al.

Quantitative, real-time, single cell analysis in tissue reveals expression dynamics of neurogenesis

Cerys S Manning, Veronica Biga, James Boyd, et al.

A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spider Parasteatoda tepidariorum

Christian L. B. Paese, Anna Schoenauer, Daniel J. Leite, et al.