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Psychiatric risk gene NT5C2 regulates protein translation in human neural progenitor cells

Rodrigo R.R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Cotel, et al.

Selected by 07 December 2018

Joanna Cross

Neuroscience

A Scube2-Shh feedback loop links morphogen release to morphogen signaling to enable scale invariant patterning of the ventral neural tube

Zach Collins, Kana Ishimatsu, Tony Tsai, et al.

Selected by 03 December 2018

Teresa Rayon

Developmental Biology

Systematic identification of human SNPs affecting regulatory element activity

Joris van Arensbergen, Ludo Pagie, Vincent FitzPatrick, et al.

Selected by 29 November 2018

Jesus Victorino

Promoter-intrinsic and local chromatin features determine gene repression in lamina-associated domains

Christ Leemans, Marloes van der Zwalm, Laura Brueckner, et al.

Selected by 28 November 2018

Carmen Adriaens, Clarice Hong

The landscape of antigen-specific T cells in human cancers

Bo Li, Longchao Liu, Jian Zhang, et al.

Selected by 19 November 2018

Rob Hynds

Cancer Biology

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient

Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, et al.

Selected by 05 November 2018

Tessa Sinnige

Biochemistry

Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells

Ina Hollerer, Juliet C Barker, Victoria Jorgensen, et al.

Selected by 30 October 2018

Clarice Hong

Genetics

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Silvia Bonàs-Guarch, Inês Cebola, et al.

Selected by 20 September 2018

Carmen Adriaens

Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Kerstin Klinkert, Nicolas Levernier, Peter Gross, et al.

AND

Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Sachin Kotak, Sukriti Kapoor

Selected by 09 September 2018

Giuliana Clemente

Cell Biology

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike B Barnkob, Hector Barbosa, et al.

Selected by 08 August 2018

Tim Fessenden

Genomics

Moving beyond P values: Everyday data analysis with estimation plots

Joses Ho, Tayfun Tumkaya, Sameer Aryal, et al.

Selected by 01 August 2018

Dey Lab

Scientific Communication and Education

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

Jessica Messier, Hongmei Chen, Zhao-Lin Cai, et al.

AND

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

Mathias Mahn, Lihi Gibor, Katayun Cohen-Kashi Malina, et al.

Selected by 22 July 2018

Mahesh Karnani

Neuroscience