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Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

Ze-Yan Yu, Yang Guo, Scott Kesteven, et al.

Discussion

Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

Claire Masson, Cyril Scandola, Jean-Yves Rinckel, et al.

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Zhipeng Deng, Camila B. Tovani, Simona Bianco, et al.

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney, et al.

Discussion

Leukocytes use endothelial membrane tunnels to extravasate the vasculature

Werner J. van der Meer, Abraham C.I. van Steen, Eike Mahlandt, et al.

Alzheimer’s Disease Patient Brain Extracts Induce Multiple Pathologies in vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery

Yanru Ji, Xiaoling Chen, Meek Connor Joseph, et al.

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Marco De Donatis, et al.

Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

Vasundhara Rao, Benjamin Grädel, Lucien Hinderling, et al.

How the liver contributes to stomach warming in the endothermic white shark Carcharodon carcharias

David C. Bernvi, Geremy Cliff

Discussion

Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

Alessandro Palma, Monica Ballarino

Discussion

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Rohith Krishna, Jue Wang, Woody Ahern, et al.

Discussion

Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis

Ziqiang P. Li, Hortense Moreau, Jules D. Petit, et al.

AND

Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants

Jessica Pérez-Sancho, Marija Smokvarska, Marie Glavier, et al.